Running a Stop Sign

MDA Quest Magazine | April 2005

PTC124 sticks to ribosomes — the cells’ protein factories — and prompts them to interpret a premature stop codon as a normal codon. Instead of aborting assembly of the protein, the ribosome inserts a protein building block — an amino acid — and continues making a complete protein chain until it encounters the normal termination codon, which the ribosome correctly interprets as a stop. read story

A Key in Search of a Lock

HHMI Bulletin | September 2003

One of Sheng Ding’s favorite activities outside the lab is scrambling up the twisted granite boulders of Southern California’s Joshua Tree National Park. By finding just the right combination of grips, foot placements, and body English, Ding can mold his body to the cracks and outcroppings, surmounting virtually any obstacle he encounters.  read in full issue (pdf)