Protein Disposal: Gumming Up the Works

HHMI Bulletin | September 2005

For a cell, destroying proteins is as essential as building them. The job of mincing proteins is performed by enzymatic machines called proteasomes. “Proteasomes affect almost all biological processes in the cell,” Verma says. By their deliberate destruction of regulatory proteins, they orchestrate activities from cell division to cell death. read in full issue (pdf)